China Conditionally Approves MSD's Molnupiravir for COVID-19 Treatment

by Grace Wang Jan 05, 2023

On Dec. 29, 2022, China National Medical Products Administration (NMPA) conditionally approved Merck Sharp & Dohme (MSD)’s Molnupiravir Capsules (brand name: Lagevrio) for COVID-19 treatment. 

The antiviral small-molecule drug is approved for treating patients who have mild-to-moderate COVID-19 infections and high risks to develop into severe conditions. The risks can be advanced age, obesity or overweightness, chronic kidney disease, diabetes, severe cardiovascular disease, chronic obstructive pulmonary disease (COPD), active cancer, etc. 

MSD has authorized Sinopharm Group with the exclusive right to import and sell Lagevrio in the mainland Chinese market.

Lagevrio’s price in China has not been revealed. In the US, one course costs 700 USD (circa 4,818 yuan).

By Jan. 31, 2023, China NMPA has approved six COVID-19 treatments:


Administra-tion Route

Marketing Authorization Holder

Approval Date

Price for One Course

Within Basic Insurance

Without Basic Insurance


Romlusevimab Combination Therapy (BRII-196/BRII-198)


Brii Biosciences

Dec. 8, 2021

Brii Biosciences revealed the price scope: 10,000 yuan


Nirmatrelvir Tablets and Ritonavir Tablets (Paxlovid)



Feb 11, 2022

1,890 yuan until Mar. 31, 2023

2,300 yuan

Azvudine Tablets


Genuine Biotech

July 25, 2022

350 yuan

540 yuan

Molnupiravir Capsules (Lagevrio)



Dec. 29, 2022

1,500 yuan


Simnotrelvir Tablets / Ritonavir Tablets (Xian Nuo Xin)



Jan. 29, 2023

750 yuan




Shanghai Vinnerna Biosciences (joint venture of Junshi Biosciences and Suzhou Wangshan Wangshui Biomedicine)

Jan. 29, 2023

Not revealed

Not revealed

Updated on Jan. 31, 2023


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Grace Wang
ChemLinked Regulatory Analyst / Editor
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